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STEVEN A. SOPER
William L. & Patricia Senn, Jr. Professor of Chemistry
Department of Chemistry
Louisiana State University
Baton Rouge, LA 70803
Phone: (225) 578-1527
Fax: (225) 578-3458
E-mail: chsope@lsu.edu | |
Research Interests:
Prof. Soper is developing a suite of polymer-based microfabricated systems for applications in genomics, including DNA sequencing and molecular diagnostics. Research efforts have also been initiated toward fabricating polymer microsystems for protein analyses. Several research focus areas include, near-IR laser-induced fluorescence; micro-capillary zone and gel electrophoresis; solid-phase microextraction of genomic and proteomic materials; single cell analyses and; integration of nanostructures into microfluidic networks.
Representative Publications:
Single Pair FRET Generated from Molecular Beacon Probes for the Real-Time Analysis of Low Abundant Mutations, M. Wabuyele, W. Stryjewski, Y.-Wei Cheng, F. Barany, H. Farquar, R.P. Hammer and S.A. Soper, JACS 125 (2003) 6937.
Fluorescence Multiplexing with Both Time-Resolved and Spectral Discrimination Capabilities using a Near-IR Microscope, L. Zhu, W. Stryjewski, S. Lassiter, S.A. Soper, Anal. Chem. 75 (2003) 2280.
Solid Phase Reversible Immobilization in Microfluidic Chips for the Purification of Dye-Labeled DNA Sequencing Fragment, Y. Zu, B. Vaidya, R.L. McCarley and S.A. Soper, Anal. Chem. 75 (2003) 2975.
Microarrays Assembled in Microfluidic Chips Fabricated form Poly(methylmethacrylate) for the Detection of Low Abundant Mutations, Y. Wang, B. Vaidya, Y.-Wei Cheng, F. Barany, H.D. Farquar, R.P. Hammer and S.A. Soper, Anal. Chem. (2002) 1130.
Asymmetrical, Water Soluble Phthalocyanine (Pc) Dyes for Covalent Labeling of Oligonucleotides. R.P. Hammer, C.V. Owens, S. Haung, C. Sayes and S.A. Soper, Bioconj. Chem. 13 (2002) 1244.
Microelectromechnical Systems (MEMS) Fabricated in Polymeric Materials: Applications in Chemistry and Life Sciences. S.A. Soper, S.M. Ford, S. Qi, R.L. McCarley, K. Kelly and M.C. Murphy, Anal. Chem.72 (2000) 642A.
WEB LINK: http://chemistry.lsu.edu/chem/facultypages/soper/soper.php | |